OUR WORK

We prioritise integrative, cutting-edge research, and seek to engage patients and clinicians.

RESEARCH PROJECTS

AUTOREGULATE-NONCARDIAC

Setting: Major noncardiac surgery
Objective: To assess the feasibility and potential clinical implications of cerebral autoregulation-based precision BP monitoring in patients at cardiovascular, renal and neurological risk undergoing major noncardiac surgery
Study design: Multicenter, prospective cohort study and precision medicine research platform
Participating centers: University Hospital Basel, HOCH Health Ostschweiz St. Gallen, Bern University Hospital
Status: Recruiting
Full study name: Association of Intraoperative Blood Pressure Excursions Below Cerebral Autoregulatory Boundaries With Organ Injury Following Major Noncardiac Surgery (AUTOREGULATE-NONCARDIAC)
Study registration: ClinicalTrials.gov NCT05336864
Support: This study is being supported by the Swiss Society for Anaesthesiology and Perioperative Medicine.

PUBLICATIONS

Wanner PM, Vogt AP, Filipovic M, Steiner LA. Intraoperative hypotension and postoperative outcomes: just the tip of the iceberg. Comment on Br J Anaesth 2023; 131: 823–31. Br J Anaesth. 2024. In press.